Vanessa Hollingshead shot her first Half-Hour Comedy Special for Comedy Central in  February 2004.

She performed in the Montreal Just For Laughs tour with Kevin Pollak, and appeared in the original pilot of the AJ Benza Show on E!

Vanessa is a favorite at Comedy Central, and was a guest host on NBC's Later. She was featured on Tough Crowd, Dateline, & Oxygen. She parodied the film, Nurse Betty on Canned Ham, and has performed in New Joke City.

She was in the critically acclaimed film Ghost Dog, directed by Jim Jarmusch, has performed on the The Jim Bruer Show, Comedy Central's Premium Blend and NBC's Louie Anderson Comedy Showcase.

She has also toured the Middle East for a month. Now, she can be seen a little closer to home in New York City at Comic Strip Live, Stand Up New York, Caroline's, The Boston Comedy Club, Gotham, and The Comedy Cellar.