In 1990, Shawn Wayans first appeared on "In Living Color". Along with his brother, Shawn Wayans created and starred in the sitcom "The Wayans Bros." and co-wrote, co-executive produced and starred in the feature "Don't Be a Menace to South Central While Drinking Your Juice in the Hood". Wayans guest-starred on episodes of "MacGyver" and "Hangin' with Mr. Cooper" and provided the voice of Toof for the animated children's series "Waynehead".

You may recognize Wayans from his first movie appearance in a gang drama "New Blood." He co-starred with Marlon in hit films directed by their older brother Keenan: "Scary Movie" and "White Chicks".