Brendon Small is a comedian and co-creator, writer, star, and music writer for UPN's and Cartoon Network's Home Movies.

In Home Movies, he portrayed the lead, an 8-year-old aspiring filmmaker, also named Brendon Small, and a number of other minor characters. Early episodes of the show featured Squigglevision, a style made famous by the cartoon Dr. Katz, Professional Therapist, produced by Soup2Nuts.

In April 2005, the Sci Fi Channel announced Small's latest show, Barbarian Chronicles, a half-hour animated comedy. It will be produced by Small and Worldwide Pants Incorporated. Small is also co-producer, co-writer, composer and actor for the Adult Swim series Metalocalypse. He has also voiced a number of roles in Season 2 of The Venture Bros.